Adrenal decision support
Incidental adrenal mass
Separate oncologic disease from a true incidentaloma, then select the least burdensome evidence-supported next step.
Current or previous extra-adrenal malignancy?
This answer deliberately comes first; oncologic lesions use a different pretest probability and pathway.
Evidence register
What governs this draft
Formal recommendations and emerging evidence.
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Evidence register
What governs this draft
Formal recommendations and emerging evidence are kept visibly separate. Source links must be rechecked before publication.
Noncontrast CT or MRI first; washout CT is conditional only when further imaging is required.
Open source ↗ESE/ENSAT 2023European Society of Endocrinology Clinical Practice GuidelineFormal guideline · Endocrine Society endorsedPrimary detailed management, hormonal, oncologic, follow-up and special-population pathway.
Open source ↗CUA 2023Canadian Urological Association Adrenal Incidentaloma GuidelineFormal Canadian management guidelineCanadian definitions, multidisciplinary assessment and management context.
Open source ↗Seow et al. 2025Washed up: the end of an era for adrenal incidentaloma CTCritical review · emerging evidenceEvidence questioning washout CT and proposing a ≤20 HU / ≤4 cm no-follow-up category for true incidentalomas.
Open source ↗